منابع مشابه
Neural plasticity in schizophrenia.
No current biological hypothesis can assimilate the genetic, environmental, and clinical features of schizophrenia. If, as some authors contend, environmental factors have important effects on the course of schizophrenia, then a fruitful research concern may be the adaptation of neuronal circuitry to environmental changes. The plasticity of neuronal connections has been studied by subjecting an...
متن کاملDysfunctional neural plasticity in patients with schizophrenia.
CONTEXT Neural plasticity in the human cortex involves a reorganization of synaptic connections in an effort to adapt to a changing environment. In schizophrenia, dysfunctional neural plasticity has been proposed as a key pathophysiological mechanism. OBJECTIVE To evaluate neural plasticity in unmedicated and medicated patients with schizophrenia compared with healthy subjects. DESIGN Neura...
متن کاملNeural Synchrony and Neural Plasticity in Tinnitus
1. Most individuals with chronic tinnitus have highfrequency hearing loss, induced by noise exposure, otological disease, or the aging process. Physiological evidence suggests that in such individuals, tinnitus is likely caused not by irritative processes that persist in the ear after cochlear injury, but by changes that occur in central auditory pathways when the ear is partly disconnected fro...
متن کاملSynaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia
Synaptic plasticity alters the strength of information flow between presynaptic and postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic neuron will lead to an action potential in a postsynaptic neuron. As such, synaptic plasticity and pathological changes in synaptic plasticity impact the synaptic computation which controls the information flow through ...
متن کاملAbnormal neural synchrony in schizophrenia.
Schizophrenia has been conceptualized as a failure of cognitive integration, and abnormalities in neural circuitry (particularly inhibitory interneurons) have been proposed as a basis for this disorder. We used measures of phase locking and phase coherence in the scalp-recorded electroencephalogram to examine the synchronization of neural circuits in schizophrenia. Compared with matched control...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 1985
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/11.2.191